Nicotine zoo li e-luam yeeb tshwm sim hauv Asmeskas kev lag luam. FDA teb: Peb tau tshuaj xyuas lawv cov kev pheej hmoo

Nicotine zoo li e-luam yeeb tshwm sim hauv Asmeskas kev lag luam. FDA teb: Peb tau tshuaj xyuas lawv cov kev pheej hmoo

Kev tshawb fawb yav dhau los los ntawm Yale University tau taw qhia tias qee cov e-luam yeeb muaj cov tshuaj nicotine analogs uas yuav tsis paub txog kev noj qab haus huv. Cov tshuaj no yuav tau ua txhaum FDA txoj cai thiab ua rau muaj kev pheej hmoo rau cov tub ntxhais hluas lub hlwb kev loj hlob, kev txawj ntse thiab kev nco. FDA tau hais tias nws yuav siv tag nrho cov peev txheej los tiv thaiv pej xeem, tshwj xeeb tshaj yog cov tub ntxhais hluas, los ntawm cov khoom lag luam uas tsim kev puas tsuaj.

Raws li Newsweek thaum Lub Yim Hli 12, kev tshawb fawb yav dhau los los ntawm Yale University tau hais tias qee cov e-luam yeeb yuav muaj cov tshuaj nicotine zoo li tsis paub txog kev noj qab haus huv.

Cov nicotine analogs cuam tshuam nrog receptors hauv lub hlwb yam tsis tau txwv lossis tshuaj xyuas los ntawm FDA. Raws li qhov tshwm sim, cov khoom lag luam no tau ua lag luam raws li "tseem ceeb uas txaus siab rau cov hluas" thiab tsis txhob them se rau haus luam yeeb.

Ib tus kws tshaj lij FDA tau hais tias cov tshuaj tshiab no tuaj yeem muaj zog dua li nicotine thiab tuaj yeem cuam tshuam rau cov tub ntxhais hluas lub hlwb kev loj hlob, kev kawm muaj peev xwm thiab kev nco.

Jim McKinney, tus kws tshaj lij kev lag luam pej xeem ntawm FDA, tau hais rau Newsweek, "FDA tab tom saib qhov no los ntawm tag nrho cov koom haum saib xyuas thiab yuav txuas ntxiv siv tag nrho cov peev txheej hauv nws txoj cai los tiv thaiv pej xeem, tshwj xeeb tshaj yog Asmeskas cov tub ntxhais hluas, los ntawm kev quav tshuaj. cov khoom uas tuaj yeem ua phem rau lawv txoj kev noj qab haus huv. " McKinney tau sau tseg tias thaum xav tau kev tshawb fawb ntxiv, qee cov ntaub ntawv tawm tshiab qhia tias cov tshuaj nicotine analogs no yuav muaj zog dua li nicotine, uas twb muaj kev quav yeeb quav tshuaj, thiab tuaj yeem hloov cov tub ntxhais hluas lub hlwb thiab muaj kev cuam tshuam ntev. Nicotine analogs yog cov tshuaj uas muaj cov qauv zoo ib yam li nicotine thiab yog li ntawd lub hom phiaj tib yam receptors hauv lub hlwb. Piv txwv suav nrog 6-methyl nicotine thiab nicotinamide. Kev tshawb fawb nas pom tau tias 6-methyl nicotine tej zaum yuav muaj tshuaj lom ntau dua li nicotine. Tsis tas li ntawd, vim hais tias cov tshuaj no tsis raug rau cov kev txwv nruj ntawm cov tshuaj nicotine ib txwm muaj, cov khoom xyaw uas tau teev nyob rau hauv daim ntawv lo tsis tas yuav phim cov khoom xyaw tiag tiag hauv cov khoom. Dr. Hanno Erythropel, tus kws tshawb fawb tshawb fawb ntawm Yale Tsev Kawm Ntawv Tshuaj Kho Mob, tau hais hauv nqe lus hais tias, "Yuav kom ua tiav, cov tuam txhab tau sim ua kom tsis txhob muaj kev tswj hwm thaum lawv tshaj tawm cov khoom tshiab nrog cov tshuaj nicotine uas tsis paub txog kev noj qab haus huv thiab kev quav yeeb quav tshuaj." Nyob rau hauv ib txoj kev tshawb fawb luam tawm nyob rau hauv phau ntawv journal JAMA Network, tus kws tshawb fawb thiab nws cov npoj yaig tau tshuaj xyuas ob lub e-luam yeeb thiab e-luam yeeb cov khoom lag luam hauv khw. Thawj cov khoom lag luam, Spree Bar, tau sau tias muaj 5% 6-methyl nicotine (50 mg / g), thaum cov khoom thib ob, Nic-Safe, raug kuaj hauv plaub qhov ntau ntxiv - 0, 12, 24 thiab 36 mg / ml. Cov txiaj ntsig tau pom tias ob qho khoom lag luam tsis sib haum nrog cov khoom xyaw uas tau teev tseg ntawm lawv cov ntawv. Spree Bar yeej muaj 90% tsawg dua 6-methyl nicotine dua li kev tshaj tawm, thaum Nic-Safe muaj cov ntsiab lus qis ntawm 6-methyl nicotine yam tsis tau raug cim kom meej rau ntawm daim ntawv lo (tsis suav nrog cov khoom tsis muaj nicotinamide kuaj). FDA tus kws tshaj lij McKinney tau hais tias,

" Feem ntau, FDA tsis hais txog cov kev tshawb fawb tshwj xeeb, tab sis theej suav tias yog ib feem ntawm cov pov thawj kom nkag siab txog cov teeb meem tshwj xeeb thiab pab ua tiav nws lub luag haujlwm ntawm kev tiv thaiv pej xeem kev noj qab haus huv. Hais txog nicotine analogs, FDA tau paub tias muaj cov tuam txhab uas tau tshaj tawm tias tau tsim cov khoom lag luam uas yuav muaj cov khoom sib txuas uas muaj cov qauv tshuaj lossis cov khoom sib txawv ntawm nicotine. "